Biomimetic, Polymeric Transistor-based Biosensor Technology

Jim Chih-Min Cheng

EECS Department
University of California, Berkeley
Technical Report No. UCB/EECS-2009-171
December 15, 2009

http://www2.eecs.berkeley.edu/Pubs/TechRpts/2009/EECS-2009-171.pdf

The goal of this research is the creation of robust, flexible, polymer sensors and circuits fabricated partially from the low cost biopolymer, chitosan, the deacetylated form of chitin which is the second most abundant polyssacharide in nature. Chitin is found in crustaceans, insects, bacteria and fungi. The sensors will detect diatomic gases and DNA to more complex macro molecules (e.g. exotoxins) in a fluidic or dry environment. Polymer-nanoparticle (e.g. Ge) hybrid films allow for development of robust polymer thin-film transistors and, with optimization of the hybrid film, sensitive photodetectors. These transistors may be developed into gas or chemical sensors through functionalization of the polymer active layer or dielectric with proteins specific to a target analyte. This technology will enable the development of integrated polymer sensors and electronics which are low-cost, robust and highly versatile due to the replacement of semiconductor, dielectric and possibly metal layers with polymers and minimal thermal budget.

Advisor: Albert Pisano


BibTeX citation:

@phdthesis{Cheng:EECS-2009-171,
    Author = {Cheng, Jim Chih-Min},
    Title = {Biomimetic, Polymeric Transistor-based Biosensor Technology},
    School = {EECS Department, University of California, Berkeley},
    Year = {2009},
    Month = {Dec},
    URL = {http://www2.eecs.berkeley.edu/Pubs/TechRpts/2009/EECS-2009-171.html},
    Number = {UCB/EECS-2009-171},
    Abstract = {The goal of this research is the creation of robust, flexible, polymer sensors and circuits fabricated partially from the low cost biopolymer, chitosan, the deacetylated form of chitin which is the second most abundant polyssacharide in nature. Chitin is found in crustaceans, insects, bacteria and fungi. The sensors will detect diatomic gases and DNA to more complex macro molecules (e.g. exotoxins) in a fluidic or dry environment. Polymer-nanoparticle (e.g. Ge) hybrid films allow for development of robust polymer thin-film transistors and, with optimization of the hybrid film, sensitive photodetectors. These transistors may be developed into gas or chemical sensors through functionalization of the polymer active layer or dielectric with proteins specific to a target analyte. This technology will enable the development of integrated polymer sensors and electronics which are low-cost, robust and highly versatile due to the replacement of semiconductor, dielectric and possibly metal layers with polymers and minimal thermal budget.}
}

EndNote citation:

%0 Thesis
%A Cheng, Jim Chih-Min
%T Biomimetic, Polymeric Transistor-based Biosensor Technology
%I EECS Department, University of California, Berkeley
%D 2009
%8 December 15
%@ UCB/EECS-2009-171
%U http://www2.eecs.berkeley.edu/Pubs/TechRpts/2009/EECS-2009-171.html
%F Cheng:EECS-2009-171