A Compartmental Lateral Inhibition System to Generate Contrasting Patterns

Ana Sofia Rufino Ferreira and Justin Hsia and Murat Arcak

EECS Department, University of California, Berkeley

Technical Report No. UCB/EECS-2015-173

July 17, 2015

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http://www2.eecs.berkeley.edu/Pubs/TechRpts/2015/Archive/EECS-2015-173.pdf

We propose a lateral inhibition system and analyze contrasting patterns of gene expression. The system consists of a set of compartments interconnected by channels. Each compartment contains a colony of cells that produce diffusible molecules to be detected by the neighboring colonies. Each cell is equipped with an inhibitory circuit that reduces its production when the detected signal is sufficiently strong. We characterize the parameter range in which steady-state patterns emerge.

BibTeX citation:

@techreport{Rufino Ferreira:EECS-2015-173,
    Author= {Rufino Ferreira, Ana Sofia and Hsia, Justin and Arcak, Murat},
    Title= {A Compartmental Lateral Inhibition System to Generate Contrasting Patterns},
    Year= {2015},
    Month= {Jul},
    Url= {http://www2.eecs.berkeley.edu/Pubs/TechRpts/2015/EECS-2015-173.html},
    Number= {UCB/EECS-2015-173},
    Abstract= {We propose a lateral inhibition system and analyze contrasting patterns of gene expression. The system consists of a set of compartments interconnected by channels. Each compartment contains a colony of cells that produce diffusible molecules to be detected by the neighboring colonies. Each cell is equipped with an inhibitory circuit that reduces its production when the detected signal is sufficiently strong. We characterize the parameter range in which steady-state patterns emerge.},
}

EndNote citation:

%0 Report
%A Rufino Ferreira, Ana Sofia 
%A Hsia, Justin 
%A Arcak, Murat 
%T A Compartmental Lateral Inhibition System to Generate Contrasting Patterns
%I EECS Department, University of California, Berkeley
%D 2015
%8 July 17
%@ UCB/EECS-2015-173
%U http://www2.eecs.berkeley.edu/Pubs/TechRpts/2015/EECS-2015-173.html
%F Rufino Ferreira:EECS-2015-173